Capparis Spinosa as an Alternative Nanoscience Medicine in Treatment of Cancer (A New Aspect of Cancer Treatment)

DOI:

https://doi.org/10.36371/port.2024.1.10

Authors

  • Ali A. H. Aljeboory College of Pharmacy, Uruk University, Baghdad, Iraq.
  • Rafid M. Hashim College of Pharmacy, Uruk University, Baghdad, Iraq.
  • Reem G. Hussein College of Pharmacy, Uruk University, Baghdad, Iraq.
  • Yahya Y. Z. Farid College of Pharmacy, Uruk University, Baghdad, Iraq.

Because of its high number of bioactive constituents in Capparis Spinosa  especially polyphenolic compounds. We have studied the extraction and identification of active constituents of bioorganic solvents polar and non-polar we have managed to identify new qualities and quantities of alkaloids from residue of chloroformic extract and separate three groups of alkaloid including tertiary - quaternary strong base alkaloid and classify the obtained individual alkaloids three groups weakly bases alkaloids, alkaloids of medium basicity, strongly bases alkaloid we found promising quantity of alkaloids in Capparis Spinosa and we tried experimental pharmacological and Biological studies of these alkaloids on cancer infected animals we got promising result as we are going to mention in our manuscript. This promising result support that the natural product evidence will continue to be important in the following areas of discovery of new drugs and to find a solution for the problem of cancer and viral incurable diseases.

Keywords:

Caper, Capparis Spinosa, Alkaloid, Nano technology, Capparisin alkaloid Vincristine

[1] IBN Sina (Avicenna), Canon medicine, Capparis Spinosa As a drug for malignant diseases. 1020.

[2] Bonina F, Puglia C, Ventura D, 2002. In vitro antioxidant and in vivo photoprotective effects of a lyophilized extract of Capparis spinosa L. buds. J Cosmet Sci 53: 321–336.

[3] Tlili N, Khaldi A, Triki S, Munné-Bosch S. 2010. Phenolic compounds and vitamin antioxidants of caper (Capparis spinosa). Plant Foods Hum Nutr 65: 260–265.

[4] Gull T, Anwar F, Sultana B, Alcayde MAC, Nouman W. 2015. Capparis species: A potential source of bioactives and highvalue components: a review. Ind Crops Prod 67: 81–96.

[5] Harvvey A.L. Drugs from natural products, England: Ellis Horwood,1993,p 450

[6] Omar Z. Ameer 1,2, Ibraheim M. Salman1.2, Ko Jin Quek1, Mohd.Z. Asmawi2. Louranthus derrugineus: Mistletoe from Traditional Uses to Laboratory Bench. Journal of Pharmacopuncture 2015.18[1]007,018

[7] Zhang S, Hu DB, He JB, Guan KY, Zhu HJ. 2014. A novel tetrahydroquinoline acid and a new racemic benzofuranone from Capparis spinosa L., a case study of absolute configuration determination using quantum methods. Tetrahedron 70:869–873.

[8] Ali Awad Aljeboory. “Haloxylon F Salsoloidpae as an Alternative Nanoscince Medicine in Treatment of Cancer”.Acta Scientific Pharmaceutical Sciences 3.1 (2019):23-28.

[9] Arena A, Bisignano G, Pavone B, et al. 2008. Antiviral and immunomodulatory effect of a lyophilized extract of Capparis spinosa L. buds. Phytother Res 22: 313–317.

[10] Kulisic-Bilusic T, Schmöller I, Schnäbele K, Siracusa L, Ruberto G. 2012. The anticarcinogenic potential of essential oil and aqueous infusion from caper (Capparis spinosa L.) Food Chem 132: 261–267.

[11] Lee T and Chen CL. “Study on Antioxidant Activity of Echinaceea purpura L. Extract and Its Impact on Cell Viability”. African Journal of Biotechnology 8 (2009): 5097-5105.

[12] Fu XP, Wu T, Abdurahim M, et al. 2008. New spermidine alkaloids from Capparis spinosa roots. Phytochem Lett 1: 59–62.

[13] Ali Awad Hamoud Aljeboory, Nazhat Mahmood Abdlkareem Al-zubaidi. Loranthus Europaeus is an alternative medicine in treatment of cyst and mouth inflammation resulted from chemotherapy of breast cancer. IJDDT. 2020; 10. 183-186

Aljeboory , A. A. H. ., Hashim, R. M. ., Hussein, R. G. ., & Farid, Y. Y. . Z. . (2024). Capparis Spinosa as an Alternative Nanoscience Medicine in Treatment of Cancer (A New Aspect of Cancer Treatment). Journal Port Science Research, 7(1), 77–86. https://doi.org/10.36371/port.2024.1.10

Downloads

Download data is not yet available.